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Bubonic Plaguer: The 411-First and second recorded Outbreaks-Part 4
The first recorded outbreak: The first recorded epidemic ravaged the Byzantine Empire during the sixth century, and was named the Plague of Justinian after emperor Justinian I, who was infected but survived through extensive treatment.  The epidemic is estimated to have killed approximately 50 million people in the Roman Empire alone. The historian Procopius wrote, in Volume II of History of the Wars, his encounter with the plague and the effect it had on the rising empire. In the spring...

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Bubonic Plague: The 411 How is it Treated? Part 3
Several classes of antibiotics are effective in treating bubonic plague. These include aminoglycosides such as streptomycin and gentamicin, tetracyclines (especially doxycycline), and the fluoroquinolone ciprofloxacin. Mortality associated with treated cases of bubonic plague is about 1–15%, compared to a mortality of 40–60% in untreated cases. People potentially infected with the plague need immediate treatment and should be given antibiotics within 24 hours of the first symptoms to prevent death. Other treatments include oxygen, intravenous fluids, and respiratory support. People who...

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Bubonic Plague the 411 Part 2
How is Bubonic Plage contracted?  Bubonic plague is an infection of the lymphatic system, usually resulting from the bite of an infected flea, Xenopsylla cheopis (the rat flea). In very rare circumstances, as in the septicemic plague, the disease can be transmitted by direct contact with infected tissue or exposure to the cough of another human. The fleas are often found on rodents such as rats and mice, and seek out other prey when their rodent hosts die. The bacteria...

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Bubonic Plague the 411 Part 1
Bubonic plague Bubonic plague is a zoonotic disease, circulating mainly in fleas on small rodents, and is one of three types of bacterial infections caused by Yersinia pestis (formerly known as Pasteurella pestis), that belongs to the family Enterobacteriaceae. Without treatment, the bubonic plague kills about two thirds of infected humans within four days. The term bubonic plague is derived from the Greek word βουβών, meaning "groin". Swollen lymph nodes (buboes) especially occur in the armpit and groin in persons suffering...

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Bubonic Plague oubreak in Northern China
Parts of a northern Chinese city have been quarantined after state media said a man there died of bubonic plague.  China's official Xinhua News Agency said Tuesday that 151 people were under observation in the city of Yumen in Gansu province after authorities determined they had come in contact with a man who died of the plague July 16.  Investigators believe the man contracted the bacterial infection after contact with a marmot, Xinhua said. The report said all the people...

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